Virology Journal

Table 2 Predictors of eGFR changes

From: Effect of 48-week pegylated interferon α-2a or nucleos(t)ide analogue therapy on renal function in Chinese patients with chronic hepatitis B

	eGFR (CKD-EPI)			eGFR (MDRD)
	Estimate	Standard error	P value^a	Estimate	Standard error	P value^a
Age	−0.907	0.055	<0.0001	−0.933	0.122	<0.0001
Sex	1.410	1.105	0.203	4.916	2.473	0.048
HBV DNA	0.211	0.214	0.325	0.502	0.573	0.382
ALT	−0.006	0.004	0.102	−0.014	0.009	0.146
AST	0.006	0.005	0.254	0.014	0.013	0.296
BUN	−0.492	0.107	<0.0001	−1.028	0.266	0.0001
ADV	−14.522	1.397	<0.0001	−27.352	2.759	<0.0001
ETV	1.595	1.430	0.266	1.963	3.640	0.590
PEG-IFN-α-2a	2.766	1.306	0.035	7.365	3.496	0.036

^aResults from the linear mixed effects model for repeated measures. LdT therapy was set as reference

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ISSN: 1743-422X

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