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Table 2 Predictors of eGFR changes

From: Effect of 48-week pegylated interferon α-2a or nucleos(t)ide analogue therapy on renal function in Chinese patients with chronic hepatitis B

  eGFR (CKD-EPI) eGFR (MDRD)
Estimate Standard error P valuea Estimate Standard error P valuea
Age −0.907 0.055 <0.0001 −0.933 0.122 <0.0001
Sex 1.410 1.105 0.203 4.916 2.473 0.048
HBV DNA 0.211 0.214 0.325 0.502 0.573 0.382
ALT −0.006 0.004 0.102 −0.014 0.009 0.146
AST 0.006 0.005 0.254 0.014 0.013 0.296
BUN −0.492 0.107 <0.0001 −1.028 0.266 0.0001
ADV −14.522 1.397 <0.0001 −27.352 2.759 <0.0001
ETV 1.595 1.430 0.266 1.963 3.640 0.590
PEG-IFN-α-2a 2.766 1.306 0.035 7.365 3.496 0.036
  1. aResults from the linear mixed effects model for repeated measures. LdT therapy was set as reference