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Table 4 Average PNGs per isolate for each subtype, nucleic acid source and viral tropism

From: Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART

  Mean PNGs, Number of isolates; % of n
Number of isolates, (% of Total) All Patterns NXT Pattern NXS Pattern NNX (S) T Pattern
Subtype
Subtype A1, n = 36 (65.4) 11.11, 36; 100 7.19, 36; 100 3.78, 36; 100 0.14, 4; 11.1
A1r recombinants n = 5 (9.1) 10.80, 5; 100 6.80, 5; 100 3.80, 5; 100 0.20, 1; 20
Subtype A2, n = 4 (7.3) 10.75, 4; 100 7.75, 4; 100 3, 4; 100 0, 0; 0
Subtype C, n = 5 (9.1) 11.2, 5; 100 7.4, 5; 100 3.8, 5; 100 0, 0; 0
Subtype D, n = 5 (9.1) 12.4, 5; 100 8.4, 5; 100 3.8, 5; 100 0.2, 1; 20
Tropism
CCR5, n = 42 (76.4) 11.02, 42; 100 7.21, 42; 100 3.64, 42; 100 0.17, 5; 100
CXCR4, n = 13 (23.6) 11.69, 13; 100 7.69, 13; 100 4, 13; 100 0
Nucleic Acid Source
DNA, n = 40 (72.7) 11.6 a, 40; 100 7.68 a, 40; 100 3.85, 40; 100 0.08, 2; 5
RNA, n = 15 (27.3) 10.07 a, 15; 100 6.4 a, 15; 100 3.4, 15; 100 0.27, 3; 20
Total, n = 55 (100) 11.18, 55; 100 7.33, 55; 100 3.73, 55; 100 0.13, 5; 9.1
  1. Key: A1R: recombinants of A1 (A1A2, n = 1; A1D, n = 3;& A1A2D, n = 1); aSignificantly different between DNA (cellular) and (RNA) extracellular viral isolates for the NXT (p = 0.016), and for all the patterns combined (p = 0.011)