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Table 2 Associations of co-receptor tropism by various methods of assignment, with HIV subtype

From: Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART

 

Subtype: Number of isolates, (proportion (%)

Total

χ 2; p-value

A1

A1R

A2

C

D

WebPSSM

CCR5

32 (88.9)

7 (100)

2 (50)

5 (100)

3 (60)

49 (86)

0.05

CXCR4

4 (11.1)

0 (0)

2 (50)

0 (0)

2 (40)

8 (14)

 

Total

36 (100)

7 (100)

4 (100)

5 (100)

5 (100)

57 (100)

 

Raymond

CCR5

28 (77.8)

6 (85.7)

2 (50)

5 (100)

1 (20)

42 (73.7)

0.024

CXCR4

8 (22.2)

1 (14.3)

2 (50)

0 (0)

4 (80)

15 (26.3)

 

Total

36 (100)

7 (100)

4 (100)

5 (100)

5 (100)

57 (100)

 

Esbjörnsson

CCR5

25 (69.4)

6 (85.7)

2 (50)

4 (80)

2 (40)

39 (68.4)

0.435

CXCR4

11 (30.6)

1 (14.3)

2 (50)

1 (20)

3 (60)

18 (21.6)

 

Total

36 (100)

7 (100)

4 (100)

5 (100)

5 (100)

57 (100)

 

Phenoseq

CCR5

30 (83.3)

6 (85.7)

4 (100)

5 (100)

3 (60)

48 (84.2)

0.416

CXCR4

6 (16.7)

1 (14.3)

0 (100)

`

2 (40]

9 (15.8)

 

Total

36 (100)

7 (100)

4 (100)

5 (100)

5 (100)

57 (100)

 

G2PFPR10

CCR5

29 (80.6)

6 (85.7)

2 (50)

5 (100)

1 (20)

43 (75.4)

0.016

CXCR4

7 (19.4)

1 (14.3)

2 (50)

0 (0)

4 (80)

14 (24.6)

 

Total

36 (100)

7 (100)

4 (100)

5 (100)

5 (100)

57 (100)

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