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Fig. 1 | Virology Journal

Fig. 1

From: miR-3156-3p is downregulated in HPV-positive cervical cancer and performs as a tumor-suppressive miRNA

Fig. 1

miR-3156-3p was aberrantly expressed in HR-HPV infected cervical cancer. a The transfection efficiency was tested by western blotting, which revealed that the transfected cells successfully expressed the E6, −E7, or -E6/E7 proteins. b-c From the microarray results, miR-3156-3p was selected as an aberrantly expressed miRNA in HPV16 E6- and E7-integrated HT-3. d The downregulation of miR-3156-3p was validated in HPV16 E6- and E7-integrated HT-3 and C-33A cells using qRT-PCR. e miR-3156-3p expression in clinical samples was evaluated using qRT-PCR. f miR-3156-3p expression in HPV16-positive and HPV18-positive clinical samples were evaluated using qRT-PCR. RNU6 served as the endogenous control for miRNAs. (**p < 0.01, *p < 0.05)

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Virology Journal

ISSN: 1743-422X