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Fig. 4 | Virology Journal

Fig. 4

From: Dendritic cells, macrophages, NK and CD8+ T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B

Fig. 4

IFN-β expression occurs in the TG of both WT and TLR2/9−/− animals after HSV-1 infection. Mice were infected with 106 p.f.u. of HSV-1, euthanized on the 5th day post infection, and the TGs were collected for mRNAs expression analysis by qPCR. The results use arbitrary units for the ratio of target gene mRNA to endogenous control HPRT mRNA. Data are representative of two independent experiments with similar results. KO = TLR2/9−/− mice. Bars show the means ± SEM. * p < 0.05. n = 4–8 mice/group

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