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Fig. 2 | Virology Journal

Fig. 2

From: Coxsackievirus B4 vertical transmission in a murine model

Fig. 2

Histopathological changes in offspring born to dams inoculated with CV-B4 E2. Pancreas, Heart, spleen and small intestine sections of six offspring (each three born to one different dam) from each of control dams and dams inoculated with CV-B4 E2, either at day 10G or 17G, were analyzed by hematoxylin/eosin staining at different p.i. times. Histopathological changes were found only in one pancreas of an offspring born to a dam inoculated at day 17G and sampled 30 days post-partum (b). Inflammatory foci and fatty degeneration of acini are indicated by little and large arrows, respectively. No anomalies were observed in all other analyzed sections. Representative microscopic observation of a pancreas section from a negative control offspring taken at day 30 post-partum (a). Gr ×400

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