Parameter | Days post-infection | |||
---|---|---|---|---|
2 | 4 | 6 | 8 | |
Hemorrhage | ||||
Infectiona | 0.87 ± 0.35 | 2.27 ± 0.45 | 2.12 ± 0.75 | 0.42 ± 0.5 |
Infection + Calcitriolb | 0.78 ± 0.44 | 2.53 ± 0.51* | 3.05 ± 0.58** | 0.96 ± 0.81** |
Alveolar and interstitial edema | ||||
Infectiona | 1 ± 0.53 | 1.82 ± 0.59 | 2.08 ± 0.86 | 0.96 ± 0.53 |
Infection + Calcitriolb | 1.11 ± 0.78 | 3.03 ± 0.64** | 2.45 ± 0.6* | 0.93 ± 0.38 |
Margination and infiltration | ||||
Infectiona | 1.62 ± 0.52 | 2.77 ± 0.43 | 2.59 ± 0.67 | 1.73 ± 0.45 |
Infection + Calcitriolb | 1.44 ± 0.53 | 3.25 ± 0.64* | 3.5 ± 0.51** | 1.52 ± 0.51 |
Alveolar collapse | ||||
Infectiona | 1.75 ± 0.46 | 2.68 ± 0.48 | 2.96 ± 0.76 | 1.69 ± 0.47 |
Infection + Calcitriolb | 1.22 ± 0.44 | 3.25 ± 0.52* | 3.18 ± 0.5 | 1.37 ± 0.49 |
Total lung injury score | ||||
Infectiona | 5.25 ± 1.16 | 9.54 ± 1.22 | 9.75 ± 2.38 | 4.81 ± 1.52 |
Infection + Calcitriolb | 4.55 ± 1.67 | 12.1 ± 1.54** | 12.2 ± 1.18** | 4.78 ± 1.25 |