TLR2 2258 G>A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus

Table 4 Multiple-SNP variants for TLR2, TLR4 and TLR9 polymorphisms and the occurrence of congenital HCMV infection

TLR gene’s polymorphisms	Multiple-SNP^a variant	Prevalence rates of multiple-SNP variants		OR^b (95% CI^c)	P-value^d
TLR gene’s polymorphisms	Multiple-SNP^a variant	Infected cases	Uninfected controls	OR^b (95% CI^c)	P-value^d
TLR2 2258 G>A – TLR4 896 C>T	GA	0.850	0.874	1.00
	GG	0.025	0.109	0.39 (0.06–2.59)	0.330
	AA	0.125	0.016	8.81 (0.93–83.12)	0.063
TLR2 2258 G>A – TLR4 1196 C>T	GC	0.875	0.859	1.00
TLR2 2258 G>A – TLR4 1196 C>T	AC	0.125	0.016	8.03 (0.85–75.63)	0.075
TLR2 2258 G>A – TLR9 2848 G>A	GA	0.400	0.576	1.00
	GG	0.475	0.408	1.62 (0.58–4.53)	0.360
	AA	0.125	0.016	11.58 (1.19–112.59)	0.040

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