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Table 3 Single-SNP analysis of the relationship between TLR2 2258 G>A polymorphism and congenital HCMV infection

From: TLR2 2258 G>A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus

A.

Genotype

Genotype frequencies; n (%)a

ORb (95% CI)c

P-valued

Infected cases

Controls

GG

15 (75.0%)

30 (96.8%)

1.00

0.018

GA

5 (25.0%)

1 (3.2%)

10.00 (1.07–93.44)

B.

Genotype

Genotype frequencies; n (%)a

ORb (95% CI)c

P-valued

Symptomatic cases

Asymptomatic cases

GG

9 (81.8%)

6 (66.7%)

1.00

0.440

GA

2 (18.2%)

3 (33.3%)

0.44 (0.06–3.51)

  1. The prevalence rates of genotypes in TLR2 SNP were compared between infected and uninfected fetuses and newborns (A) as well as symptomatic and asymptomatic offsprings with congenital cytomegaly (B)
  2. P ≤ 0.050 is considered as significant
  3. a n number of tested fetuses and newborns
  4. b OR odds ratio
  5. c 95% CI, confidence interval
  6. dlogistic regression model