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Table 2 Comparison of age, gender and cytokine concentrations between severe and mild SFTS patientsa

From: Correlation of cytokine level with the severity of severe fever with thrombocytopenia syndrome

Characteristic

Mild patients (n = 36)

Severe patients (n = 14)

p Value

Sex, male, n (%)

13 (36.1)

4 (28.6)

0.613

Age, year

59.5 (49.3–65.0)

67 (62.0–73.5)

0.003

TNF-α

1.2 (0.7–1.6)

1.3 (0.5–4.0)

0.314

G-CSF

6.9 (5.3–10.6)

20.1 (11.7–49.1)

0.001

IFN-γ

8.8 (3.9–25.1)

54.3 (6.2–90.4)

0.005

IFN-α

11.0 (5.3–18.8)

26.9 (14.3–138.3)

0.001

MIP-1α

12.1 (2.5–30.7)

56.4 (20.6–222.0)

0.001

IL-6

18.3 (7.9–45.8)

121.2 (47.5–272.4)

0.001

MCP-1

141.7 (85.4–339.9)

227.8 (118.6–1185.4)

0.115

IL-10

1188.7 (87.7–2436.2)

3917.0 (106.9–11025.9)

0.210

IP-10

2178.0 (1260.8–3715.6)

5385.2 (3362.3–8394.3)

0.003

RANTES

4855.4 (3070.1–7739.9)

4195.5 (2728.6–6199.0)

0.612

  1. Unit: pg/ml; aValues are listed as median range unless otherwise noted