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Table 1 The efficiency of BBR and pirodavir against EV71 in vitro

From: Berberine inhibits enterovirus 71 replication by downregulating the MEK/ERK signaling pathway and autophagy

 

Pirodavir

BBR

TC50 (μM)

IC50 (μM)

SI

TC50 (μM)

IC50 (μM)

SI

EV71(H)

27.49 ± 5.18

0.41 ± 0

67.05

73.10 ± 0.79

8.55 ± 0

8.55

EV71(SHZH98)

27.49 ± 5.18

0.26 ± 0.05

105.73

73.10 ± 0.79

10.25 ± 7.24

7.13

EV71(JS-52)

27.49 ± 5.18

0.47 ± 0.08

58.49

73.10 ± 0.79

7.43 ± 1.59

9.84

EV71(BrCr)

27.49 ± 5.18

0.22 ± 0.11

124.95

73.10 ± 0.79

7.43 ± 1.59

9.84

  1. Values provided in this table represent the mean of three independent experiments