Derivation of chicken induced pluripotent stem cells tolerant to Newcastle disease virus-induced lysis through multiple rounds of infection

Susta, Leonardo; He, Ying; Hutcheson, Jessica M.; Lu, Yangqing; West, Franklin D.; Stice, Steven L.; Yu, Ping; Abdo, Zaid; Afonso, Claudio L.

doi:10.1186/s12985-016-0659-3

Virology Journal

Table 2 List of pathways upregulated and downregulated between selected, persistently infected, and naïve BA3NI ciPSCs

From: Derivation of chicken induced pluripotent stem cells tolerant to Newcastle disease virus-induced lysis through multiple rounds of infection

BA3NI-I9-C1 compared to BA3NI-I0		BA3NI-I6 compared to BA3NI-I9-C1		BA3NI-I6 compared to BA3NI-I0
Upregulated	Downregulated	Upregulated	Downregulated	Upregulated	Downregulated
Al, ASP, GLU Metabolism	Fatty Acid Elongation	Fatty Acid Elongation	Al, ASP, GLU Metabolism		Ribosome Biogenesis in Eukaryotes
Val, Leu, Iso degradation	Steroid Hormone Biosynthesis	Steroid Hormone Biosynthesis	Lysine degradation		Spliceosome
Lysine degradation	Oxidative Phosphorylation	Oxidative Phosphorylation	Inositol Phosphate Metabolism
Inositol Phosphate Metabolism	Pyrimidine Metabolism	Pyrimidine Metabolism	mRNA surveillance Pathway
MAPK Signalling Pathway	Glutathione Metabolism	Arginin and Proline Metabolism	MAPK Signalling Pathway
ERBB Signalling Pathway	N-Glycan Biosynthesis	Tyrosine Metabolism	ERBB Signalling Pathway
FOXO Signalling Pathway	GPI-anchor Biosynthesis	Glutathione Metabolism	FOXO Signalling Pathway
PI Signalling System	Ribosome Biogenesis in Eukaryotes	N-Glycan Biosynthesis	PI Signalling System
Oocyte Meiosis	Ribosome	Glycosaminoglycan Degradation	Oocyte Meiosis
Ubiquitin-Mediated Proteolysis	RNA polymerase	GPI Anchor Biosynthesis	Ubiquitin-Mediated Proteolysis
Endocytosis	Spliceosome	Arachidonic Acid and Metabolism	Endocytosis
mTOR signalling Pathway	Proteasome	Metabolism of Xenobiotics by Cytochrome P450	mTOR Signalling Pathway
Apoptosis	Protein Export	Ribosome	Apoptosis
Adrenergic signalling in Cardiomyocytes	Neuroactive ligand-receptor interaction	Proteasome	Adrenergic signalling in Cardiomyocytes
Vascular smooth muscle contraction	Protein Processing in Endoplasmic Reticulum	Protein Export	Vascular smooth muscle contraction
WNT Signalling Pathway	Lysosome	Neuroactive Ligand-Receptor Interaction	WNT Signalling Pathway
Dorso-Ventral Axis Formation	Phagosome	Protein Processing in Endoplasmic reticulum	Dorso-Ventral Axis Formation
VEGF Signalling Pathway	Cardiac Muscle Contraction	Lysosome	VEGF Signalling Pathway
Focal Adhesion	Cell Adhesion Molecules	Cardiac Muscle Contraction	Focal Adhesion
Tight Junction		Cell Adhesion Molecules	Adherens Junction
Gap Junction			Tight Junction
Regulation of Actin Cytoskeleton			Gap Junction
Insulin Signalling Pathway			Toll-like receptor Signalling pathway
GnRH Signalling Pathway			Jak-Stat Signalling pathway
Progesterone-mediated Oocyte maturation			Regulation of Actin Cytoskeleton
			Insulin Signalling pathway
			GnRH Signalling Pathway
			Progesterone-Mediated Oocyte Maturation
			Salmonella Infection
			Influenza A infection

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ISSN: 1743-422X

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