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Table 1 Tissue Culture Infectious Dose50 (TCID50) of EV-A71 mutants in comparison with the wild type EV-A71 strain 41

From: Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71

EV-A71 Mutants

TCID50

A158T

1.00 × 104

C475T

1.00 × 106

A486G

1.00 × 104

G487A

7.50 × 105

A5262G

3.41 × 105

Partial Deletant (PD) 5′-NTR

1.00 × 106

Positive Control (EV-A71 strain 41)

1.00 × 103

  1. RD cells were infected with the EV-A71 wild type and mutant viruses at a MOI of 0.1. The TCID50/ml values are calculated using the Reed and Muench formula determined from two independent experiments [26]
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Virology Journal

ISSN: 1743-422X