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Table 2 Nucleotide sequence mutation at L1 of 13 HPV-33 isolates

From: L1 and L2 gene polymorphisms in HPV-58 and HPV-33: implications for vaccine design and diagnosis

Sequence pattern

HPV33 L1 Nucleotide sequence

n

Sub-lineages

 

5

5

5

5

6

6

6

6

6

6

6

6

6

6

6

6

6

6

7

7

  
 

7

9

9

9

3

3

3

4

4

4

5

5

6

6

6

6

7

9

0

0

  
 

6

6

9

9

8

9

9

6

7

8

2

4

1

6

7

9

4

5

4

6

  
 

0

0

0

7

5

0

6

3

8

7

0

4

3

4

3

4

8

1

4

3

  

M12732

C

T

G

A

T

C

G

T

T

A

G

A

T

A

A

A

A

A

C

G

  

KU550663

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

39

A1

KU550664

-

C

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

4

A1

KU550665

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

C

-

-

1

A1

KU550666

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

G

-

-

-

-

1

A1

KU550667

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

A

-

2

A1

KU550668

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

A

54

A1

KU550669

-

-

-

-

-

-

-

-

-

-

-

-

C

-

-

-

-

-

-

A

1

A1

KU550670

-

-

-

-

-

-

-

-

-

-

A

-

-

-

-

-

-

-

-

A

2

A1

KU550671

-

-

-

-

G

-

-

-

-

-

-

-

-

-

-

-

-

-

-

A

1

A1

KU550672

-

-

-

-

-

-

-

-

-

C

-

-

-

-

-

-

-

-

-

-

1

A1

KU550673

-

-

-

G

-

A

A

-

-

-

-

G

-

G

-

-

-

-

-

-

4

A1

KU550674

-

-

-

-

-

A

A

C

-

-

-

G

-

G

-

-

-

-

-

-

1

A1

KU550675

A

-

A

-

-

A

-

-

C

-

-

-

C

G

G

-

C

-

-

-

13

A2

   

G

K

 

T

G

         

E

K

P

   
 

T

 

1

1

 

2

2

         

3

4

4

   

aa mutation

5

-

3

3

-

6

6

-

-

-

-

-

-

-

-

-

8

5

8

-

124

 
 

6

 

3

5

 

6

8

         

5

3

4

   
 

N

 

S

R

 

K

E

         

D

T

H

   

second struture

-

-

-

-

-

-

-

-

-

-

H

-

-

H

H

-

H

-

-

-

  
  1. Note: M12732 was used as reference. The nucleotides conserved with respect to the reference sequence are marked with a dash(-), whereas a variation position was indicated by a letter. Predicted amino acid changes were also shown. The “S” in the last row of the table means Sheet, the “H” means Helix