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Fig. 2 | Virology Journal

Fig. 2

From: The mutated tegument protein UL7 attenuates the virulence of herpes simplex virus 1 by reducing the modulation of α-4 gene transcription

Fig. 2

The mutated UL7 gene modulates viral proliferation. a Dynamic profile of the UL7-MU viral strain at 37 °C. Vero cells were infected with UL7-MU (filled circles) or HSV-1 WT (open boxes) at an MOI of 1. The supernatants and cells were harvested at the indicated time points, and the lysates were titered on Vero cells. b Morphological features of UL7-MU mutant plaques at 37 °C. Vero cells were infected with UL7-MU or HSV-1 WT at an MOI of 0.00001. The cells were fixed and stained 3 d p.i. c Dynamic profile of the UL7-MU viral strain at 34 °C. Vero cells were infected with UL7-MU (filled triangles) or HSV-1 WT (open triangles) at an MOI of 1. The supernatants and cells were harvested at the indicated time points, and the lysates were titered on Vero cells

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