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Table 1 Number of animals used in immunization experiments

From: Codon optimization of antigen coding sequences improves the immune potential of DNA vaccines against avian influenza virus H5N1 in mice and chickens

  

DNA dose

Number of animals per group

HAw/pCI

K3/pCI

GK/pCI

pCI

Mice

Experiment 1

20 μg

7

6

-

6

Experiment 2

10 μg

-

6

7

-

50 μg

-

6

6

2

Experiment 3

10 μg

-

6

5

2

Experiment 4

20 μg

-

6

6

2

Chickens

Experiment 1 (Broilers)

60 μg

8

8

-

5

Experiment 2 (Layers)

60 μg

-

6

6

2

Experiment 3 (Broilers)

60 μg

-

10

9

4

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Virology Journal

ISSN: 1743-422X