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Fig. 4 | Virology Journal

Fig. 4

From: Codon optimization of antigen coding sequences improves the immune potential of DNA vaccines against avian influenza virus H5N1 in mice and chickens

Fig. 4

Comparison of humoral responses in mice immunized with two optimized variants of DNA vaccine. The presence of anti H5 HA antibodies was monitored in sera collected from the animals on the indicated days in three independent experiments, Experiments 2, 3 and 4 (see also Table 1). The results for individuals, medians and the 10th and 90th percentiles are shown for each group. Statistically significant differences between groups K3/pCI and GK/pCI (p < 0.05) are marked by asterisks. The arrows show from which individuals the spleens have been harvested. The values in the brackets are the geometric means calculated for the K3/pCI and GK/pCI groups

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Virology Journal

ISSN: 1743-422X