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Fig. 3 | Virology Journal

Fig. 3

From: Codon optimization of antigen coding sequences improves the immune potential of DNA vaccines against avian influenza virus H5N1 in mice and chickens

Fig. 3

Comparison of humoral responses in animals immunized with two variants of the DNA vaccine. The mice (a) and chickens (b) sera was tested for the presence of the anti-H5 HA antibodies after immunization with the variant containing the wild type H5 HA (HAw/pCI) and the variant containing H5 HA optimized to the chicken codon bias (K3/pCI). The results of one-dilution ELISA for individuals, medians and the 10th and 90th percentiles are shown for each group. The number of individuals was as indicated in Table 1, in Experiment 1 for mice and chickens, respectively. The values in the brackets are the geometric means calculated for the K3/pCI and GK/pCI groups

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Virology Journal

ISSN: 1743-422X