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Fig. 5 | Virology Journal

Fig. 5

From: Isolation of dengue virus serotype 4 genotype II from a patient with high viral load and a mixed Th1/Th17 inflammatory cytokine profile in South Brazil

Fig. 5

Phylogenetic tree of dengue virus serotype 4. Phylogenetic analysis based on the complete nucleic acid sequence of a 2013 Brazilian isolate of DENV-4 (LRV13/422). The phylogenetic tree was inferred using the maximum likelihood algorithm based on the general time-reversible model with gamma-distributed rate variation and a proportion of invariable sites (GTR+I+G), as implemented in MEGA6.06. The numbers shown to the right of the nodes represent bootstrap support values >70 (1000 replicates). The tree was rooted with DENV-1 (NC_001477.1), and the branch lengths do not represent the genetic distance. The strains are labeled according to GenBank accession number/2-letter country code/year of isolation

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