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Fig. 8 | Virology Journal

Fig. 8

From: Antibodies against Lewis antigens inhibit the binding of human norovirus GII.4 virus-like particles to saliva but not to intestinal Caco-2 cells

Fig. 8

NoV VLPs bind to D-Caco-2 cells independently of H type-2 antigen expression. GII.4-2004 (v2) VLPs were added to D-Caco-2 cells after adding anti-H2 antigen. After 1 h incubation at 37 °C with an anti-H2 mAb, the cells were fixed and incubated with secondary FITC-conjugated anti-rabbit IgG (to detect VLP binding) or Texas red-conjugated anti-mouse IgG (to detect anti-H2) antibodies. No co-localization of H2 antigen expression and VLP binding was observed

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Virology Journal

ISSN: 1743-422X