Fig. 4

Blockade with anti-NoV mAbs of VLP binding to saliva samples. Microtiter plate wells were coated with saliva from a secretor individual at 1:500. Each VLP variant was preincubated with its homologous mAb before being added to the plate at 37 °C and detected with HRP-conjugated to anti-mouse IgG. All dilutions of anti-NoV antibodies reduced the binding with the homologous VLP variant compared to the controls in a dose-dependent manner. Error bars represent standard deviation