Fig. 1

Binding of NoV VLPs (GII.4-1999 (v0) and GII.4-2004 (v2) and GII.4-2006b) to porcine gastric mucin (PGM). Microtiter plates coated with PGM (10 μg/ml) or without PGM (PBS) were incubated with the different VLPs at 2 μg/ml for 1 h and processed for detection of bound VLPs by ELISA, using an anti-NoV VLP rabbit polyclonal antiserum (pAb). Binding is expressed as percentages referred to the highest OD 450 nm value obtained in duplicate assays. Error bars indicate standard deviations