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Fig. 7 | Virology Journal

Fig. 7

From: Visualizing the replicating HSV-1 virus using STED super-resolution microscopy

Fig. 7

Average distances of ICP8 and RNA Pol II Ser2P, ICP8 and RNA Pol II Ser5P, HSV-1 genome and ICP8. At early stage of replication, average distances of ICP8 and RNA Pol II Ser2P, ICP8 and RNA Pol II Ser5P, ICP8 and HSV-1 genome are 262.2 nm, 195.7 nm and 132.4 nm, respectively. Similarly, average distances of late stage of replication are 283.0 nm, 247.0 nm and 183.6 nm. Differences between early and late stages of replication (ICP8 and RNA Pol II Ser5P, ICP8 and HSV-1 genome) are significant (p valueICP8 RNA Pol II Ser5P (early and late stage) < 0.001 (***), p valueICP8 HSV-1 genome(early and late stage) < 0.001 (***)). Differences among ICP8 and RNA Pol II Ser2P, ICP8 and RNA Pol II Ser5P, ICP8 and HSV-1 genome are all significant (p valueICP8 RNA Pol II Ser2P and ICP8 RNA Pol II Ser5P (early and late stage) < 0.05 (*), p valueICP8 RNA Pol II Ser2P and ICP8 HSV-1 (early and late stage) < 0.001 (***), p valueICP8 RNA Pol II Ser5P and ICP8 HSV-1 (early and late stage) < 0.001 (***)). The data were evaluated with one-way ANOVA method

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