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Fig. 6 | Virology Journal

Fig. 6

From: Atlantic salmon (Salmo salar L.) post-smolts challenged two or nine weeks after seawater-transfer show differences in their susceptibility to salmonid alphavirus subtype 3 (SAV3)

Fig. 6

HES and IHC staining of pancreas from Phase-A post-smolts. a and b, CT group at 7 dpi; normal pancreatic tissue in Atlantic salmon with endocrine pancreatic tissue (arrow), exocrine pancreatic tissue with zymogen granules (*) and fat tissue (arrowhead) without red colour staining from IHC indicating the absence of SAV. c and d, IM group at 7 dpi; necrosis of exocrine pancreatic tissue with the presence of SAV confirmed by IHC. e and f, BI group at 7 dpi; normal appearance of pancreatic tissue, but the presence of SAV shown by IHC. g and h, IM group at 14 dpi; mononucleated cells (macrophage-like or fibroblast-like cells) replaced normal pancreatic tissue and weak staining for SAV by IHC. i and j, BI group at 14 dpi; necrosis of exocrine pancreatic tissue and strong staining for SAV by IHC. a, c, e, g, and i, HES staining. b, d, f, h, and j, IHC staining. Bar 50 μm. The insets were at 200x

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