Skip to main content

Table 1 Correlations between STK31 methylation and the different clinicopathological features of human CCs

From: Serine/threonine kinases 31(STK31) may be a novel cellular target gene for the HPV16 oncogene E7 with potential as a DNA hypomethylation biomarker in cervical cancer

Clinicopathological features N STK31 methylation p
+ -
Age 148    
<45   49 13 0.741
≥45   66 20  
Histology 102    
Squamous cell carcinoma   67 13 1.000
Adenocarcinoma   18 4  
Differentiation 146    
Well + Moderate   75 17 0.584
Poor   42 12  
Lymph node metastasis 100    
Positive   23 7 0.708
Negative   56 14  
FIGO stage 119    
IA1 ~ IIA2   50 14 0.617
IIB ~ IIIA   45 10  
Tumor size (cm) 148    
<1   40 11 0.877
≥1   75 22  
HPV16/18 134    
No(HPV-negative)   18 0 0.037
Yes   87 29  
HPV genotyping 123    
HPV16   81 19 0.711
HPV18   20 3  
Squamous cell carcinoma-Ag(SCC-Ag) 80    
Normal   24 4 1.000
High   45 7  
Neoajuvant Chemotherapy 55    
No   23 7 0.029
Yes   25 0  
Neoajuvant Chemotherapy resistance 55    
No   44 9 0.037
Yes   0 2