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Fig. 2 | Virology Journal

Fig. 2

From: Serine/threonine kinases 31(STK31) may be a novel cellular target gene for the HPV16 oncogene E7 with potential as a DNA hypomethylation biomarker in cervical cancer

Fig. 2

STK31 expression was different in the development of cervical lesions and the expression was regulated by its methylation status. a MSP and qPCR revealed that methylation status and expression of STK31 gene were different in different stages of cervical lesions. b Results of MSP and western blotting showed that demethylating agent 5-aza-dC induced STK31 expression of C33A and HT-3 cells by down-regulating its promoter/exon1 methylation status. c The effects of 5-aza-dC on STK31 gene and was concentration and time depedent

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Virology Journal

ISSN: 1743-422X