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Fig. 5 | Virology Journal

Fig. 5

From: A heat-inactivated H7N3 vaccine induces cross-reactive cellular immunity in HLA-A2.1 transgenic mice

Fig. 5

Viral load levels in the lungs of mice following infection with PR8-NPN370Q virus. Groups of mice (7/group) immunized with the HI-H7N3 virus were infected i.n. four weeks later with 3 LD50 (which corresponds to 103.7 TCID50) of PR8-NPN370Q virus. Naïve mice inoculated with PR8-NPN370Q virus served as controls. Three days and seven days after challenge, mice were sacrificed and lungs were collected for viral titration on MDCK cells. Virus titers from individual mice are presented as log10 TCID50 per ml (expressed as the mean ± SD log10TCID50/g of tissue). One of three similar experiments is shown. *P < 0.005 compared with unprimed mice

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