Fig. 3

SULT1A1 knockdown is associated with decreased viral gene expression following infection of MDMs with a replication-competent HIV-1 vector. a The same method was used as in Fig. 2a, however 100 μl (corresponding to 66.3 ng p24) HIV-1 Env + JM1186-Rluc virus was added to the cells at day 11 and luciferase and cell viability was assayed at 72 h post-infection. b HIV-1 luciferase reporter expression, SULT1A1 protein expression, and cell viability of MDMs 24 h post infection with HIV-1 Env + JM1186-RLuc.. Mean and SD shown, *** p < 0.0005 ** p < 0.005 * p < 0.05 one sample t test. Results shown are from 6 donors assayed twice. Samples with <60 % SULT1A1 knockdown and/or <65 % cell viability were not used in the analysis. All values were compared to ASN control