Subtype-gene evolutionary ratea | Genotype | tMRCAb |
---|---|---|
OC43-Spike 7.2 (5.2–9.4) |  |  |
 | all genotypes | 1952.2 (1931.0–1965.2) |
 | genotype A | 1961.8 (1955.1–1966.0) |
 | genotype B | 1991.0 (1981.4–1999.0) |
 | genotype C/D | 2001.7 (2000.1–2002.9) |
 | genotype D | 2004.5 (2003.3–2005.8) |
 | genotype E | 2009.3 (2008.3–2010.0) |
 | novel lineage 1 | 2007.5 (2006.6–2008.0) |
 | novel lineage 2 | 2010.5 (2009.5–2011.4) |
HKU1-Spike 6.2 (4.5–8.0) |  |  |
 | all genotypes | 1957.2 (1920.3–1987.5) |
 | genotype A | 1999.4 (1994.8–2002.5) |
genotype B | 2001.2 (1997.6–2003.6) | |
genotype C | 2002.3 (1999.8–2003.8) | |
HKU1-Nucleocapsid 4.3 (2.8–5.8) |  |  |
 | all genotypes | 1962.0 (1915.1–1994.8) |
genotype A | 1986.8 (1970.8–1999.0) | |
genotype B | 2002.2 (1999.4–2002.2) | |
genotype C | 2002.3 (2000.1–2003.8) |