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Table 3 Summary of results of statistical comparison between the charge of amino acid positions from R4X4 and R5 sequences

From: Statistical correlation of nonconservative substitutions of HIV gp41 variable amino acid residues with the R5X4 HIV-1 phenotype

Mann–Whitney U test
 Rank HXB2 residue Positiona p (U-test)b p (QFD = .05)c p (QFD = .10)c Location
  1 N 636 .0002 .00086 .0017 HR2
χ2 test
 Rank HXB2 residue Position p (X 2)b p (QFD = .05)c p (QFD = .10)c  
  1 N 636 .00004 .00086 .0017 HR2
  2 L 602 .00005 .0017 .0034 Loop
  3 Q 658 .0010 .0026 .0052 HR2
  4 N 809 .0050 .0034 .0068 LLP-3
  5 A 667 .0055 .0043 .0086 MPER
  6 R 841 .0078 .0052 .0104 LLP-1
  1. aResidue number is based on the sequence of HXB2 gp120
  2. bBold characters indicate positions with significant p values using QFD = .05. Normal characters indicate positions with significant p values using QFD = .1
  3. cBenjamini-Hochberg critical p values