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Table 2 Differential expression of genes belonging to the GO term “sensory organ development” in HUVEC and HSaVEC following RV infection

From: Gene expression profiling of rubella virus infected primary endothelial cells of fetal and adult origin

Gene symbol Gene title Fold change microarray (a)
   HUVEC HSaVEC
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 −4.89 n.s.
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 −4.16 n.s.
CLN8 ceroid-lipofuscinosis, neuronal 8 −8.05 n.s.
DSCAM Down syndrome cell adhesion molecule −9.98 n.s.
FGFR2 fibroblast growth factor receptor 2 −10.01 5.03
FZD3 frizzled family receptor 3 −10.00 −8.56
JAG2 jagged 2 −4.86 n.s.
−4.01
MYO3A myosin 3A −9.46 n.s.
MYO7A myosin 7A −5.65 −6.17
NHS Nance-Horan syndrome −4.35 n.s.
NOG noggin −6.68 −5.04
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 −7.70 n.s.
PDGFRA platelet-derived growth factor receptor, alpha polypeptide −6.24 n.s.
RDH10 retinol dehydrogenase 10 (all-trans) −9.00 n.s.
SLC25A27 solute carrier family 25, member 27 −16.78 n.s.
TNPO1 transportin 1 −7.66 n.s.
TRPM1 transient receptor potential cation channel, subfamily M, member 1 −7.72 −5.76
TSPAN12 tetraspanin 12 −4.42 n.s.
  1. aDisplayed are the average fold changes from three independent experiments of RV-infected cells in comparison to non-infected cells detected by the microarray that meet the selected criteria (i.e. fold change cut-off ≤ −4 and ≥ 4 and ANOVA p-value of ≤ 0.01). If a gene was detected by several different probes, all fold changes that meet the selected criteria are shown. Positions labeled n.s. where not shown to be significantly up- or down-regulated in the DNA microarray analysis