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Table 2 Differential expression of genes belonging to the GO term “sensory organ development” in HUVEC and HSaVEC following RV infection

From: Gene expression profiling of rubella virus infected primary endothelial cells of fetal and adult origin

Gene symbol Gene title Fold change microarray (a)
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 −4.89 n.s.
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 −4.16 n.s.
CLN8 ceroid-lipofuscinosis, neuronal 8 −8.05 n.s.
DSCAM Down syndrome cell adhesion molecule −9.98 n.s.
FGFR2 fibroblast growth factor receptor 2 −10.01 5.03
FZD3 frizzled family receptor 3 −10.00 −8.56
JAG2 jagged 2 −4.86 n.s.
MYO3A myosin 3A −9.46 n.s.
MYO7A myosin 7A −5.65 −6.17
NHS Nance-Horan syndrome −4.35 n.s.
NOG noggin −6.68 −5.04
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 −7.70 n.s.
PDGFRA platelet-derived growth factor receptor, alpha polypeptide −6.24 n.s.
RDH10 retinol dehydrogenase 10 (all-trans) −9.00 n.s.
SLC25A27 solute carrier family 25, member 27 −16.78 n.s.
TNPO1 transportin 1 −7.66 n.s.
TRPM1 transient receptor potential cation channel, subfamily M, member 1 −7.72 −5.76
TSPAN12 tetraspanin 12 −4.42 n.s.
  1. aDisplayed are the average fold changes from three independent experiments of RV-infected cells in comparison to non-infected cells detected by the microarray that meet the selected criteria (i.e. fold change cut-off ≤ −4 and ≥ 4 and ANOVA p-value of ≤ 0.01). If a gene was detected by several different probes, all fold changes that meet the selected criteria are shown. Positions labeled n.s. where not shown to be significantly up- or down-regulated in the DNA microarray analysis