Fig. 6

Donor-to-donor variation of sensory organ gene expression in HUVEC isolated from different donors. Two pools of HUVEC, with each pool consisting of cells from three different donors, were infected with RV at an MOI of 5 and gene expression relative to non-infected cells was quantified by qPCR 36 hpi. GAPDH was used for normalization. Bars denote mean ∆∆CT ± SEM with ∆∆CT values < 0 indicating up-regulation and ∆∆CT values > 0 indicating down-regulation. A two-tailed unpaired t-test was used to determine statistically significant differences in gene expression using ∆CT values and is indicated by an asterisk (*, p ≤ 0.05; **, p ≤ 0.01)