Fig. 6

Changes of HBV-specific CD8+ T cells, T-bet, PD-1, IFN-γand perforin in AHB. a Percentage of HBV-specific CD8+ T cells existed in the acute and recovery stages (p = 0.0343, by Wilcoxon signed rank test); b Level of T-bet in HBV-specific CD8+ T cells in the acute and recovery stages (p = 0.0156, by Wilcoxon signed rank test); c Level of PD-1 in HBV-specific CD8+ T cells in the acute and recovery stages (P = 0.0313, by Wilcoxon signed rank test); d Level of IFN-γ in HBV-specific CD8+ T cells in the acute and recovery stages (P = 0.0006, by paired t test); e Level of perforin in HBV-specific CD8+ T cells in the acute and recovery stages (P = 0.0062, by paired t test); f Representative flow cytometry data of T-bet and PD-1 expression in acute stage and recovery stage of AHB