Fig. 5
From: T-bet expression in CD8+ T cells associated with chronic hepatitis B virus infection
Correlation between percentage of T-bet + or PD-1+ HBV-specific CD8+ T cells and HBV DNA content or IFN-γ level in PBMC from CHB patients. a The percentage of T-bet + cells was negatively related to the percentage of PD-1+ cells (r = −0.8638, p < 0.0001); b The percentage of T-bet + cells was negatively related to HBV DNA (r = −0.8741, p < 0.0001); c The percentage of PD-1+ cells was positively related to HBV DNA (r = 0.8864, p < 0.0001); d The percentage of T-bet + cells was positively related to IFN-γ level (r = 0.7193, p = 0.0008); e The percentage of PD-1+ cells was negatively related to IFN-γ level (r = −0.7027, p = 0.0011), Spearman rank correlation test was used for data analysis