Table 2 Go terms of up-regulated and down-regulated miRNA target genes

Biological adhesion

17

9

1.07 %

1.65 %

Biological regulation

291

94

18.32 %

17.28 %

Cellular component organization or biogenesis

152

38

9.57 %

6.99 %

Cellular process

899

295

56.61 %

54.23 %

Developmental process

91

26

5.73 %

4.78 %

Establishment of localization

198

85

12.47 %

15.63 %

Growth

17

3

1.07 %

0.55 %

Immune system process

10

2

0.63 %

0.37 %

Localization

205

89

12.91 %

16.36 %

Locomotion

16

6

1.01 %

1.10 %

Metabolic process

875

266

55.10 %

48.90 %

Multicellular organismal process

106

34

6.68 %

6.25 %

Multi-organism process

5

2

0.31 %

0.37 %

Negative regulation of biological process

48

10

3.02 %

1.84 %

Positive regulation of biological process

31

10

1.95 %

1.84 %

Regulation of biological process

277

92

17.44 %

16.91 %

Reproduction

25

8

1.57 %

1.47 %

Reproductive process

21

6

1.32 %

1.10 %

Response to stimulus

205

73

12.91 %

13.42 %

Rhythmic process

3

1

0.19 %

0.18 %

Signaling

143

51

9.01 %

9.38 %

Single-organism process

471

171

29.66 %

31.43 %

Cell

615

198

38.73 %

36.40 %

Cell junction

17

12

1.07 %

2.21 %

Cell part

615

198

38.73 %

36.40 %

Extracellular matrix

7

3

0.44 %

0.55 %

Extracellular matrix part

4

2

0.25 %

0.37 %

Extracellular region

30

13

1.89 %

2.39 %

Extracellular region part

12

3

0.76 %

0.55 %

Macromolecular complex

294

85

18.51 %

15.63 %

Membrane

260

101

16.37 %

18.57 %

Membrane-enclosed lumen

104

23

6.55 %

4.23 %

Membrane part

171

71

10.77 %

13.05 %

Organelle

387

100

24.37 %

18.38 %

Organelle part

229

59

14.42 %

10.85 %

Synapse

12

11

0.76 %

2.02 %

Synapse part

10

9

0.63 %

1.65 %

Virion

1

1

0.06 %

0.18 %

Virion part

1

1

0.06 %

0.18 %

Antioxidant activity

5

0

0.31 %

0

Binding

906

280

57.05 %

51.47 %

Catalytic activity

905

295

56.99 %

54.23 %

Electron carrier activity

29

10

1.83 %

1.84 %

Enzyme regulator activity

42

21

2.64 %

3.86 %

Molecular transducer activity

36

15

2.27 %

2.76 %

Nucleic acid binding transcription factor activity

20

6

1.26 %

1.10 %

Protein binding transcription factor activity

15

2

0.94 %

0.37 %

Receptor activity

27

12

1.70 %

2.21 %

Structural molecule activity

27

4

1.70 %

0.74 %

Translation regulator activity

1

0

0.06 %

0

Transporter activity

81

48

5.10 %

8.82 %

Channel regulator activity

0

1

0

0.18 %

Metallochaperone activity

0

1

0

0.18 %