Fig. 3
From: Occult hepatitis B virus infection: influence of S protein variants
a. Numbers of residue changes in clones from OBI group and Control group patients within the “α” determinant of the MHR. The numbers for the 260 clones (circles) in OBI group and the 259 clones (squares) in Control group are distributed according to the numbers of residue changes in the “α” determinant. Lines and numbers above them in parentheses, means of amino acid mutation/clone in the “α” determinant; numbers on the right side of circles or squares, numbers of clones. Statistical significance was calculated using a Mann–Whitney test. b. Frequencies of residue substitutions within the S protein in isolated clones from HBsAg- negative patients (OBI group, black bars, n = 17) and HBsAg- positive patients (Control group, white bars, n = 15), analyzed in intervals of 10 amino acids each. Each bar represents the percentage of mutated residues for all clones at each interval of 10 amino acids per group. *, P < 0.05