Fig. 6

Alignment of ISAV segment 6 HPR amino acid sequences containing the deletion. The alignment was adjusted manually as all known alignment software packages cannot align amino acid sequences in such a delicate and complex area in Fig. 5. The alignment confirms the three ISAV HPR patterns in Fig. 5: The first pattern VT12212012-1068 belongs to ISAV-HPR0; the second pattern VT03282012-222-C and VT02142012-90 belongs to ISAV-HPR7b; the third pattern with 36 isolates and shown in VT05252012-337G belongs to ISAV-HPR5. Similarly to Fig. 5, only 6 of the 36 sequences in the third pattern are included in Fig. 6