Table 1 Summary of patient characteristics and virological findings

Age, years, median, (range)

27 (16–60)

34 (18–59)

0.02

Gender (M/F)

11/5

40/28

0.57

Genotype (A/B/C/D)

3/4/2/7

15/7/3/43

–

Serum HBV DNA^a

8.30 ± 0.38

4.30 ± 0.14

<0.0001

Serum HBsAg^b

4.40 ± 0.18

3.41 ± 0.11

<0.0001

HBV DNA/HBsAg

3.90 ± 0.29

0.89 ± 0.14

<0.0001

ALT/ULN, median, (range)

1.37 (0.68–8.6)

0.72 (0.24–12.38)

<0.001

cccDNA^c

−0.70 ± 0.20

−2.67 ± 0.10

<0.0001

S RNA^c/cccDNA^c

1.65 ± 0.20

2.73 ± 0.11

<0.0001

pgRNA^c/cccDNA^c

2.04 ± 0.12

1.50 ± 0.11

<0.01

pgRNA^c/S RNA^c

0.39 ± 0.23

−1.22 ± 0.07

<0.0001