Fig. 4From: Mechanisms downstream of reverse transcription reduce serum levels of HBV DNA but not of HBsAg in chronic hepatitis B virus infectionFlowchart showing differences in intrahepatic and serum viral load between HBeAg-positive and HBeAg-negative patients. Δe indicates mean difference between levels in HBeAg-positive and HBeAg-negative patients. Three novel findings are pointed out: (i) a greater reduction of HBV DNA in serum as compared with in the liver; (ii) an unchanged HBsAg/S RNA ratio; (iii) an increased S-RNA/cccDNA ratio, in HBeAg-negative as compared with HBeAg-positive patientsBack to article page