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Fig. 5 | Virology Journal

Fig. 5

From: Sequencing of emerging canine distemper virus strain reveals new distinct genetic lineage in the United States associated with disease in wildlife and domestic canine populations

Fig. 5

Serum neutralization assay. Five adult research dogs were vaccinated with a modified live virus vaccine approximately 1 year after vaccination with the same vaccine. CDV titers were determined by serum neutralization using either the new strain or the vaccine strain (Nobi). Viruses were each used at 100 TCID50 per well and the results are reported as the means of three replicates. The experiments were repeated, and the results for both experiments are included. The titers were not significantly different between pre-vaccination and post-vaccination when evaluating titers with the new strain. There was a significant difference between pre- and post-vaccination titers when testing with the vaccine strain, suggesting the memory response was specific for the vaccine virus

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Virology Journal

ISSN: 1743-422X