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Table 2 Concentrations that inhibit 50 % of infection and the selective indexes of compounds 2 and 10 with respect to the four dengue virus serotypes

From: Quinic acid derivatives inhibit dengue virus replication in vitro

 

2

10

 

IC50 ± SD (ÎŒM)

SI

IC50 ± SD (ÎŒM)

SI

DENV-1

6.9 ± 3.6

3.6

6.5 ± 0.2

4.5

DENV-2

10.4 ± 3.9

2.4

8.7 ± 2.3

3.3

DENV-3

10.3 ± 3.1

2.4

10.3 ± 3.8

2.8

DENV-4

9.23 ± 3.7

2.7

10.8 ± 1.7

2.7

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Virology Journal

ISSN: 1743-422X