Fig. 5From: Quinic acid derivatives inhibit dengue virus replication in vitroDENV subgenomic replicon system. Huh7.5 cells were transfected with either dengue virus serotype-1 replicon RepDV1 or dengue virus serotype-3 replicon RepDV3 RNA, and after one hour elapsed they were treated with compounds 2 and 10 at the NTC. After 72 h, the cells were submitted to FACS analysis (anti-NS3 staining using the monoclonal antibody 1722). Pseudocolor plots (a) and histograms showing the mean fluorescent intensity (MFI) (b) are representative of one experiment, and relative percentages as meanâ±âstandard error (SE) from three independent experiments (c). In parallel, cell viability was evaluated by neutral red assay (d). *pâ<â0.05 compared to the untreated controlBack to article page