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Fig. 5 | Virology Journal

Fig. 5

From: Quinic acid derivatives inhibit dengue virus replication in vitro

Fig. 5

DENV subgenomic replicon system. Huh7.5 cells were transfected with either dengue virus serotype-1 replicon RepDV1 or dengue virus serotype-3 replicon RepDV3 RNA, and after one hour elapsed they were treated with compounds 2 and 10 at the NTC. After 72 h, the cells were submitted to FACS analysis (anti-NS3 staining using the monoclonal antibody 1722). Pseudocolor plots (a) and histograms showing the mean fluorescent intensity (MFI) (b) are representative of one experiment, and relative percentages as mean ± standard error (SE) from three independent experiments (c). In parallel, cell viability was evaluated by neutral red assay (d). *p < 0.05 compared to the untreated control

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