Skip to main content
Fig. 1 | Virology Journal

Fig. 1

From: Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine

Fig. 1

Matrix-M™ enhances homologous HAI responses induced by TVV. Mice (n = 8/group) were immunized with TVV (−) containing 3μg HA per strain or TVV + MM (+). Three weeks later, serum samples were obtained and tested for HAI responses against vaccine homologous H1N1 A/California/07/09, H3N2 A/Perth/16/09 (A/Victoria/210/09-like), and B/Brisbane/60/08 (B/Victoria lineage). Black bars indicate medians of log2 transformed titers. (*p < 0.05, **p < 0.01, ***p < 0.001, compared to the vehicle control group (PBS) using Wilcoxon’s rank-sum test adjusted for multiple comparisons). Results of the statistical comparisons between one and two immunizations and between immunizations with TVV and TVV + MM are summarized in Additional file 1: Table S1

Back to article page