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Table 6 Polymorphic sites in the HCV-4 NS3 protease not resistance-associated found in this study

From: Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C

aPositions

bSubtype 4

aPositions

bSubtype 4

12

G12/R (1)

98

T98/A (1)

13

L13/M (8)

102

A102/S (8)

14

F14/L (8)

105

Y105/F (7)

15

S15/G (7)

114

I114/V (8)

18

V18/I (8)

122

T122/N (1)

24

R24/K (1)

127

L127/I (5)

33

V33/I (4)

133

S133/A (1)

47

A47/S (3)

134

I134/T (8)

48

V48/I (7)

147

M147/L (8)

61

A61/S (8)

150

R150/A (8)

92

R92/K (8)

172

V172/I (1)

95

A95/T (1)

179

M179/A (1)

  1. a The residues are reported as in the wild-type HCV-1a sequence
  2. b The number of patients with mutant HCV strains is indicated in brackets
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Virology Journal

ISSN: 1743-422X