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Table 5 Polymorphic sites not associated with resistance to DAAs in the HCV 2c NS3 protease

From: Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C

Position NS3a

Subtype 2cb

15

D15G/S (9)

33

V33I (3)

35

V35I (1)

134

S134T (4)

146

P146S (1)

177

V177I (1)

  1. aThe residues are reported as in the wild-type HCV-1a sequence
  2. bThe number of patients with mutant HCV strains is indicated in brackets