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Fig. 2 | Virology Journal

Fig. 2

From: Actinobacillus pleuropneumoniae induces SJPL cell cycle arrest in G2/M-phase and inhibits porcine reproductive and respiratory syndrome virus replication

Fig. 2

AppΔapxICΔapxIIC culture supernatant blocks SJPL cell cycle in G2/M-phase but not MARC-145 cell cycle. a Representative experiment of SJPL and MARC-145 cell cycle profile analysis; DMEM, nocodazole and aphidicolin as controls are compared to the A. pleuropneumoniae culture supernatant. G1: Gap-1 phase; S: synthesis phase; G2/M: Gap-2 and mitotic phases. b Distribution of cell cycle phases after SJPL cells treatments with DMEM or AppΔapxICΔapxIIC culture supernatant. The experiments were repeated at least 4 times. Asterisks indicated significant differences between untreated cells and cells treated with AppΔapxICΔapxIIC culture supernatant. ***P ≤ 0.001, values are presented as ± standard error of the mean (SEM)

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