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Fig. 2 | Virology Journal

Fig. 2

From: HAM/TSP-derived HTLV-1-infected T cell lines promote morphological and functional changes in human astrocytes cell lines: possible role in the enhanced T cells recruitment into Central Nervous System

Fig. 2

Co-culture of HTLV-1-infected T cell lines with astrocytoma cell lines result in rapid syncytium formation. HTLV-1-infected T cell lines (CIB and C91PL) were co-cultured with astrocyte (U251 and U87) and non-astrocytic (Hela) cell lines for up to 20 h. After 20 h cells were fixed, stained with Giemsa and observed on light microscopy. Syncytia were characterized by presence of large, irregular and multinucleated cells and were observed in panels of co-culture of CIB with U251 (b–c) and U87 (f–g) and also in the panels of co-culture of C91PL with U251 (d), but not in the co-culture of CEM (h) or CIB (i) with HeLa cell line. Original magnifications: ×200 (a–b, e–f and g–h) and × 400 (c–d and g)

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Virology Journal

ISSN: 1743-422X