Fig. 2

Individual and average cytokine concentrations in serum over time. Individual cytokine concentrations in serum are indicated per each time point post onset of disease: blue squares indicate individual non-fatal cases and red dots indicate individual fatal cases. Average concentrations at each time points are indicated by open blue squares (non-fatal) and red circles (fatal). The continuous green line indicates the average concentration in negative control samples (RVF naïve individuals) and thus has no bearing on the days indicated on the x-axis. Certain days are represented by only one data point per data set, in which case no medians are shown (days 1, 4, 6, 10 and 13). For days where less than three samples were available per dataset, averages are shown instead of medians. Note: because of the 1:4 dilution of serum for the cytokine analysis, a “0 pg/ml” value represents a limit of detection rather than absolute absence of the detected protein