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Table 1 General characteristics of the studied cohort

From: Hepatitis B surface gene variants isolated from blood donors with overt and occult HBV infection in north eastern Egypt

 

Total (n = 126)

HBsAg-/

anti-HBc+ (n = 44)

HBsAg+ (n = 82)

P-value

Age (Years) Mean ± SD

29.1 ± 7.1

32.9 ± 6.1

28.0 ± 7

NS

Gender (M)

118 (93.7)

44 (100 %)

74 (90 %)

0.049

ALT (IU/L)

18.8 ± 10.6

18.6 ± 13.9

19 ± 7.2

NS

HBV DNA S region (+)

84 (66.7 %)

10 (22.7 %)

74 (90 %)

0.0001

MHR Substitutions (%)

34/84 (40.5)

7/10 (50)a

27/74 (37.8)

0.5

T115S

7/84 (8.3)

0

7/74 (9.5)

NS

P120T/S

2/84 (2.3)

0

2/74 (2.7)

NS

T125M

2/84 (2.3)

2/10 (20)

0

0.01

P127T

1/84 (1.2)

1/10 (10)

0

NS

Q129R

9/84 (10.7)

4/10 (40)

5 (5.8)

0.01

K141R

1/84 (1.2)

0

1 (1.4)

NS

S143L/T

12/84 (14.3)

0

12 (16.2)

NS

  1. aTwo MHR mutants were present simultaneously in 2 cases; OCU18 and OCU158