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Fig. 3 | Virology Journal

Fig. 3

From: Up-regulation of A20/ABIN1 contributes to inefficient M1 macrophage polarization during Hepatitis C virus infection

Fig. 3

HCV antigen stimulation suppresses NF-κB activity in polarized M1 macrophages. a The expressions of A20/ABIN1/TAX1BP1 were distinctively influenced by each antigen. Core protein highly increases A20 levels and NS3/4A enhances ABIN1 expression. TAX1BP1 shows a slight reduction trend by NS3/4A stimulation. b NF-κB activity was down regulated by HCV antigen stimulation, with regard to p65 phosphorylation

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